GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | BMPR1A | chr10:88516396-88684944:+ | -0.23 | -6.01 | 3.77E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | CLDN2 | chrX:106143394-106174091:+ | 0.27 | 6.14 | 1.77E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.89 | 1.76E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | EPDR1 | chr7:37960163-37991539:+ | 0.31 | 6.8 | 3.13E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | GGT5 | chr22:24615623-24641110:- | 0.26 | 5.98 | 4.36E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | LRRC42 | chr1:54412037-54433839:+ | -0.24 | -6.3 | 6.82E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.61 | 1.03E-16 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7028661 | chr9:100538470 | PLCE1 | chr10:95753746-96088146:+ | 0.28 | 6.43 | 3.1E-10 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | BMPR1A | chr10:88516396-88684944:+ | -0.24 | -6.19 | 1.26E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | CLDN2 | chrX:106143394-106174091:+ | 0.26 | 6.08 | 2.48E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | EFNB2 | chr13:107142098-107187337:- | -0.25 | -5.87 | 7.95E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | EML5 | chr14:89081205-89259157:- | 0.3 | 6.83 | 2.65E-11 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | EPDR1 | chr7:37960163-37991539:+ | 0.32 | 7.23 | 1.88E-12 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | NKX6-1 | chr4:85414436-85419387:- | 0.5 | 8.61 | 1.08E-16 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |
| THCA | trans | rs965513 | 1 | rs7030241 | chr9:100550375 | PLCE1 | chr10:95753746-96088146:+ | 0.26 | 5.99 | 4.14E-9 | Thyroid cancer (Papillary, radiation-related);Thyroid cancer |